Reproductive Immunology: Open Access

Abstract

AIM

We evaluated the prevalence of LA enlargement (LAE) and the relationship with left ventricular (LV) mass and diastolic function in subjects hypertensive inducedleft ventricular hypertrophy referred to an echocardiographic study for routine clinical indications.

METHOD

100 patients underwent a comprehensive echo-Doppler examination. LAE and LV hypertrophy (LVH) were defined as LA volume index (LAVI) >29 ml/m2 and LV mass index (LVMI) >50 g/m2 respectively. Abnormalities of LV relaxation and LV filling were diagnosed by age-related thresholds of early mitral flow velocity to Ei ratio (E/Ei) ≥16, respectively.

RESULTS

According to our study, we found that the measurement of E/Ei derived from medial mitral annulus estimated better .It also supports that E/Ei is one of the best Doppler echocardiographic parameter to estimate diastolic function. E/ Ei and LAVI were estimated for patients with Concentric Left ventricular hypertrophy as well as normal patients. In our study, LAVI correlates better with Grade of diastolic dysfunction.LAVI is greater in patients with high E/Ei ratio. Age, height, weight was found to be associated with high LAVI. Other studies have shown that the older age group patients are more prone to left atrial enlargement. Patient with Diabetes mellitus (DM), hypertension (HTN) ,Chronic Kidney Disease (CKD) are associated with diastolic dysfunction, that shows raised E/Ei Therefore noninvasive tissue Doppler measurement of E/Ei can be used to stratify the risk of the patients.