People living with severe mental illness (SMI) with physical health faces one of the greatest health inequality gap. The aim of this work is to consider the evidence in relation to healthcare provision for people with SMI, identify gaps in knowledge, and provide an overview of the field. People with severe mental illness (SMI) have more physical comorbidity than the general population. The physical health disorders which have high prevalence in people with severe mental illness are mainly Nutritional and metabolic diseases, Cardiovascular diseases, Viral diseases, Respiratory tract diseases, Musculoskeletal diseases, Sexual dysfunction, pregnancy complications, Stomatognathic diseases, and Obesity related diseases. Furthermore, contributing factors are considered that impact on the physical health of these people, such as psychotropic medications (antipsychotics, antidepressants and mood stabilizers), individual lifestyle choices (e.g., smoking, diet, and exercise), psychiatric symptoms, as well as disparities in the health care. Life expectancy tends to decrease by 15-25 years among those people. People with mental health problems are two to three times more likely to smoke cigarettes, consume alcohol, and use cannabis and other illegal drugs observed by (Tidey and Miller, 2015) and (Hartz et al, 2014).To improve mental health of individuals and society at large includes the promotion of mental well-being, prevention of mental disorders, protection of human rights, and care of people suffering from mental disorders.